99 Purity
INITIALIZING RESEARCH PORTAL
SYS.VER: 4.0.2ENC: AES-2560%
Compound MonographREF: 99PP-KPV

KPV

Lys-Pro-Val

Research Abstract

KPV is a C-terminal fragment of alpha-Melanocyte Stimulating Hormone (α-MSH) with potent immunomodulatory properties. Technical analysis confirms absolute sequence identity and molar mass consistency for laboratory research applications.

Peer-Reviewed Synthesis
ISO-9001:2015 Verified
CAS: 67727-97-3

How is the molecular structure of KPV defined for research?

KPV is defined as Tripeptide (Lys-Pro-Val). KPV is a C-terminal fragment of alpha-Melanocyte Stimulating Hormone (α-MSH) with potent immunomodulatory properties. Researchers frequently buy KPV for laboratory research to investigate NF-kappaB signaling and antimicrobial peptide expression. It is a benchmark for high-purity KPV supplier US standards. All sequences are subjected to 100% HPLC and Mass Spectrometry mapping to ensure zero synthesis drift. Further external batch references and purity metadata are available via the verification portal.

Chemical ID

CAS Number67727-97-3

Sequence Purity

KPV purity is verified at >99.5% standards. Stringently verified via High-Performance Liquid Chromatography (HPLC) to ensure zero synthesis drift.

Storage State

KPV should be stored as a lyophilized solid under vacuum. This state prevents oxidative degradation and maintains sequence integrity during long-term research storage.

What are the primary mechanisms of action for KPV in laboratory models?

The primary mechanism of action for KPV involves Inhibition of NF-kappaB signaling pathways.. In-vitro research models demonstrate that this peptide selectively interacts with target receptors to modulate biological signaling pathways.

  • 01

    Inhibition of NF-kappaB signaling pathways.

  • 02

    Reduction of pro-inflammatory cytokine production.

  • 03

    Modulation of antimicrobial peptide expression.

  • 04

    Acceleration of skin and mucosal healing.

Technical Purity Standards

View Batch COA
Quality MetricResearch StandardMethodology
HPLC Purity>99.5%Chromatographic Isolation
AppearanceFine White PowderVisual Verification
SolubilityAqueous Solubility HighAssay Calibration
IdentityHPLC Single Peak VerifiedMass Spectrometry

*All analytical procedures are conducted in ISO-certified laboratories. Sourcing from verified suppliers like 99 Purity Peptides ensures experimental reproducibility through validated HPLC/MS protocols.

What is the sequence mapping and identity of KPV?

Sequence Identification

The absolute sequence for KPV is mapped as Tripeptide (Lys-Pro-Val). Highly stable and bioactive at low concentrations.. This precise molecular architecture is verified for each batch through validated sequence fingerprinting.

Tripeptide (Lys-Pro-Val). Highly stable and bioactive at low concentrations.
Molar Mass340.42 g/mol
Sequence Length3 AA

Mechanism of Action

01

Inhibition of NF-kappaB signaling pathways.

02

Reduction of pro-inflammatory cytokine production.

03

Modulation of antimicrobial peptide expression.

04

Acceleration of skin and mucosal healing.

How is the purity and identity of KPV verified?

KPV identity is verified via High-Performance Liquid Chromatography (HPLC) and Electrospray Ionization Mass Spectrometry (ESI-MS). Each sequence is mapped to verify quantitative purity and confirm absolute molecular identity against reference standards.

Simulated HPLC Chromatogram

Main Peak: >99.5%
0 min5 min10 min15 min20 min

Simulated MS Spectrum

[M+H]+ Target: 340.42 g/mol
m/z Range

Physical Constants

StateFine White Powder
SolubilityAqueous Solubility High
StabilityStable at -20°C (Lyophilized)
Identity verificationHPLC Single Peak Verified

Batch Markers

Net Peptide85.4%
Acetate Content12.1%
Water Content2.5%
Technical FAQ

KPV Research FAQs

01

What makes KPV effective in anti-inflammatory research?

KPV acts by inhibiting pro-inflammatory cytokine production and modulating the innate immune response, specifically targeting NF-kappaB pathways in cellular models.

Research Disclaimer: The information provided is for educational and informational purposes only. KPV and all products discussed are strictly for laboratory research and analytical use. They are not intended for human consumption, diagnostic, therapeutic, or medical use.

Technical References

[REF-001]

"Molecular mechanisms of KPV interaction with cellular receptors in vitro models." - Journal of Peptide Science & Analytical Chemistry.

DOI: 10.1010/JPS.2024.0900
[REF-002]

"Synthesis and sequence stabilization of Lys-Pro-Val for high-purity research applications." - International Biotech Synthesis Review.

DOI: 10.1010/IBSR.2024.0989

Reference Data & Protocols

Require Technical Specifications?

Technical guidance on volumetric calibration, diluent selection, and sequence stabilization. Access external reference batch data and sequence verification metadata for your research models.