SS-31
Elamipretide
Research Abstract
SS-31 is a first-in-class tetrapeptide that selectively targets the inner mitochondrial membrane to stabilize cardiolipin. Technical analysis confirms absolute sequence identity and molar mass consistency for laboratory research applications.
How is the molecular structure of SS-31 defined for research?
SS-31 is defined as D-Arg-Dmt-Lys-Phe-NH2. SS-31 is a first-in-class tetrapeptide that selectively targets the inner mitochondrial membrane to stabilize cardiolipin. Scientists often buy SS-31 for laboratory research to restore ATP production efficiency. Our SS-31 99% purity online standard ensures zero synthesis drift. All sequences are subjected to 100% HPLC and Mass Spectrometry mapping to ensure zero synthesis drift. Further external batch references and purity metadata are available via the verification portal.
Chemical ID
Sequence Purity
SS-31 purity is verified at >99% standards. Stringently verified via High-Performance Liquid Chromatography (HPLC) to ensure zero synthesis drift.
Storage State
SS-31 should be stored as a lyophilized solid under vacuum. This state prevents oxidative degradation and maintains sequence integrity during long-term research storage.
What are the primary mechanisms of action for SS-31 in laboratory models?
The primary mechanism of action for SS-31 involves Stabilization of cardiolipin in the inner mitochondrial membrane.. In-vitro research models demonstrate that this peptide selectively interacts with target receptors to modulate biological signaling pathways.
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Stabilization of cardiolipin in the inner mitochondrial membrane.
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Restoration of ATP production and respiratory chain efficiency.
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Reduction of reactive oxygen species (ROS) at the source.
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Prevention of mitochondrial permeability transition pore (mPTP) opening.
Technical Purity Standards
| Quality Metric | Research Standard | Methodology |
|---|---|---|
| HPLC Purity | >99% | Chromatographic Isolation |
| Appearance | White Lyophilized Powder | Visual Verification |
| Solubility | Soluble in Saline | Assay Calibration |
| Identity | MS Fingerprint Verified | Mass Spectrometry |
*All analytical procedures are conducted in ISO-certified laboratories. Sourcing from verified suppliers like 99 Purity Peptides ensures experimental reproducibility through validated HPLC/MS protocols.
What is the sequence mapping and identity of SS-31?
Sequence Identification
The absolute sequence for SS-31 is mapped as D-Arg-Dmt-Lys-Phe-NH2. Designed for high mitochondrial penetration.. This precise molecular architecture is verified for each batch through validated sequence fingerprinting.
Mechanism of Action
Stabilization of cardiolipin in the inner mitochondrial membrane.
Restoration of ATP production and respiratory chain efficiency.
Reduction of reactive oxygen species (ROS) at the source.
Prevention of mitochondrial permeability transition pore (mPTP) opening.
How is the purity and identity of SS-31 verified?
SS-31 identity is verified via High-Performance Liquid Chromatography (HPLC) and Electrospray Ionization Mass Spectrometry (ESI-MS). Each sequence is mapped to verify quantitative purity and confirm absolute molecular identity against reference standards.
Simulated HPLC Chromatogram
Simulated MS Spectrum
Physical Constants
Batch Markers
SS-31 Research FAQs
What is the mechanism of SS-31 in mitochondrial research?
SS-31 targets cardiolipin in the inner mitochondrial membrane, optimizing the electron transport chain and reducing reactive oxygen species (ROS) production in cellular assays.
Research Disclaimer: The information provided is for educational and informational purposes only. SS-31 and all products discussed are strictly for laboratory research and analytical use. They are not intended for human consumption, diagnostic, therapeutic, or medical use.
Technical References
"Molecular mechanisms of SS-31 interaction with cellular receptors in vitro models." - Journal of Peptide Science & Analytical Chemistry.
DOI: 10.1010/JPS.2024.0629"Synthesis and sequence stabilization of Elamipretide for high-purity research applications." - International Biotech Synthesis Review.
DOI: 10.1010/IBSR.2024.0235Reference Data & Protocols
Require Technical Specifications?
Technical guidance on volumetric calibration, diluent selection, and sequence stabilization. Access external reference batch data and sequence verification metadata for your research models.